CAAS XA - X-Ray Angiography Software CAAS XA slide 1 CAAS XA slide 2

CAAS XA - X-Ray Angiography Software

CAAS XA - Quantitative X-Ray Angiography Software: The gold standard in Quantitative Analysis Software

Technology and features are system/configuration dependent. Specifications subject to change without notice. Information might refer to products or modalities not yet approved in all countries.
  • Overview
  • CAAS QCA
  • CAAS QVA
  • CAAS LVA RVA
  • CAAS A-VALVE


CAAS XA - Quantitative X-Ray Angiography Software

The gold standard in Quantitative Analysis Software

The gold standard CAAS platform represents the widest range of post-processing images solutions for optimal assistance during medical diagnostics providing highly accurate and reproducible data as required by cardiologists and radiologists and optimizing assistance during the intervention. The CAAS solution develops innovative solutions that provide an answer to the need in both clinical and in research settings. The CAAS platform offers software packages for quantitative X-ray angiography image analysis with a complete range of tools allowing the performing of accurate and reproducible measurements of the dimensions of coronary arteries, peripheral blood vessels as well as left and right ventricles.


The CAAS product line for X-ray image analysis consists of several modules which offer quantification of coronary arteries, peripheral vessels and the left and right ventricle:

    Quantitative Coronary Analysis software:
  • CAAS QCA
  • CAAS QCA 2D Bifurcation
  • CAAS QCA 3D
  • CAAS QCA for Research
    Quantitative Vascular Analysis software:
  • CAAS QVA
  • CAAS QVA 3D
  • CAAS QVA for Research
    Left and Right Ventricular Analysis software:
  • CAAS LVA
  • CAAS RVA
    A-Valve Software for Aortic Valve procedures:
  • CAAS A-VALVE
  • CAAS A-VALVE qRA

About Pie Medical Imaging

Pie Medical Imaging B.V. based in Maastricht, the Netherlands, is the worldwide leading company in quantitative analysis software for cardiology and radiology and well known for the CAAS products. Pie Medical Imaging develops and delivers software solutions that drive next-generation diagnostics and research worldwide. Pie Medical Imaging is part of the Esaote group.

Technology and features are system/configuration dependent. Specifications subject to change without notice. For further details, please contact your EBIT sales representative.


CAAS QCA - Quantitative Coronary Analysis software

Optimal diagnostics and interventions with accurate and reproducible measurements

Quantitative Coronary Analysis (QCA) being highly accurate and reproducible can refine the visual estimate and provide several important measurements of the coronary anatomy. CAAS QCA (Quantitative Coronary Analysis) is the worldwide accepted standard for the assessment of coronary arterial dimensions, and to assist in the selection of the optimal balloon and stent size.


  • Automatic Reference Obstruction analysis
  • Multiple contour detection methods
  • Local Diameter analysis
  • Total Occlusion analysis
  • Minimum Luminal Diameter (MLD)
  • Reference Diameter
  • % Diameter Stenosis
  • Length stenotic segment
  • % Area stenosis at MLD
  • Reference area
  • Volume stenotic segment
  • Plaque area, volume and symmetry
  • Bifurcation angles
  • Optimal projection in CAAS QCA 3D

Technology and features are system/configuration dependent. Specifications subject to change without notice. For further details, please contact your EBIT sales representative.

CAAS QCA

CAAS QCA (Quantitative Coronary Analysis) is the worldwide accepted standard for assessment of coronary artery dimensions. Our software can assist in the selection of the optimal balloon and stent. CAAS QCA features single vessel analysis including calibration, vessel border detection and quantification of the severity of stenosis.

  • Various methods for calibration; catheter, sphere, manual or automatically calculated based on geometric information
  • Vessel border detection
  • Easy contour edits
  • Automatic and user defined reconstruction of the healthy vessel shape
  • Quantification of lesion length and percentage stenosis
  • DICOM files with single and multi-frame, monoplane and biplane images.

CAAS QCA 2D Bifurcation

With CAAS QCA 2D Bifurcation, we have developed a dedicated QCA program to assess bifurcation lesions. CAAS QCA 2D Bifurcation is an option on the standard CAAS QCA software.

Analysis of bifurcated arteries: coronary artery bifurcation lesions pose a major challenge for interventional cardiologists as percutaneous treatment of these lesions is associated with increased risks of complications. Evaluation of dedicated stenting devices, using the conventional QCA without dedicated bifurcation option, has limitations. This is due to vessel diameter changes over the bifurcation. Another complication lies in defining the true reference vessel size (healthy vessel) within the bifurcation area. You can overcome these limitations and achieve the most accurate bifurcation analysis by using CAAS QCA 2D Bifurcation

  • Treats the bifurcation as a single unambiguous object
  • Vessel border detection for bifurcations
  • Easy contour edits
  • Automatic and user defined reconstruction of the healthy vessel shape for the total bifurcation as one unambiguous object
  • Automatic calculation of bifurcation angles
  • Quantification of lesion length and percentage stenosis

CAAS QCA 3D

CAAS QCA 3D (3 dimensional Quantitative Coronary Analysis) offers 3D analysis of single and bifurcated coronary arteries. Multiple X-ray projections are used to calculate the true geometric shape in 3D space. This eliminates foreshortening and out-of-plane magnification errors. QCA3D offers improved analysis results and a clear visualization of the geometry of difficult lesions. The optional real-time co-registration with IVUS or OCT adds an angiographic roadmap to the patient’s intravascular anatomy.

  • Interactive 3D rendered view for assessment of shape
  • Full automatic calibration: this eliminates the need for manual input
  • Vessel border detection
  • Quantification of lesion length and percentage stenosis in 3D

CASS QCA for Research

CAAS QCA for Research (Quantitative Coronary Analysis) has specific additional functionality for both single vessel and bifurcation analysis. For example, stent analysis models, which feature quick comparison of implanted (bifurcation) stents in pre-, post- and follow-up studies. In research QCA is the most frequently used analysis tool for evaluation of novel interventional methods, pharmaceuticals and devices. Various methods for calibration; catheter, sphere, manual or automatically calculated based on geometric information

  • Vessel border detection
  • Easy contour edits
  • Automatic and user defined reconstruction of the healthy vessel shape
  • Quantification of lesion length and percentage stenosis
  • Drug Eluting Stent analysis: evaluation of restenosis and edge effects with a dedicated segment model
  • User Defined Subsegment analysis: divide the vessel in multiple sub segments
  • Independent evaluation of multiple segments within one vessel part
  • Dedicated models for bifurcation analysis: 6 and 11 segments


Quantitative Vascular Analysis software for Clinical and Research Use

Mayor benefits in clinical routine with CAAS QVA

CAAS QVA (Quantitative Vascular Analysis) offers fast and intuitive analysis of peripheral vessels such as the abdominal aorta and the carotid, renal, iliac and femoral arteries.
The CAAS QVA application features single vessel analysis including calibration, contour detection and quantification of the severity of stenosis. The software is able to automatically reconstruct the healthy vessel contour in stenotic segments.
User defined subsegment (UDS) analysis allows the user to select a region of interest within the vessel under study.

Technology and features are system/configuration dependent. Specifications subject to change without notice. For further details, please contact your EBIT sales representative.

CAAS QVA

CAAS QVA (Quantitative Vascular Analysis) offers fast and intuitive analysis of peripheral vessels such as the abdominal aorta and the carotid, renal, iliac and femoral arteries. CAAS QVA features single vessel analysis including calibration, vessel border detection and quantification of severity of stenosis.

  • Various methods for calibration; catheter, sphere, manual or automatically calculated based on geometric information
  • Vessel border detection based on novel algorithms.
  • Easy contour edits
  • Automatic and user defined reconstruction of the healthy vessel shape
  • Quantification of lesion length and percentage stenosis

CAAS QVA 3D

CAAS QVA 3D (3 dimensional Quantitative Vascular Analysis) offers fast and intuitive analysis of peripheral vessels such as the abdominal aorta and the carotid, renal, iliac and femoral arteries. CAAS QVA 3D features single vessel analysis including full automatic calibration, vessel border detection and quantification of severity of stenosis according to its true 3D geometric shape.

  • Elimination of foreshortening and out-of-plane magnification errors
  • Interactive 3D rendered view for assessment of shape
  • Full automatic calibration: reconstruction in 3D space allows for an optimal automatic calculation of the pixel size for each position of the artery. This eliminates the need for manual input
  • Vessel border detection based on novel algorithms.
  • Easy contour edits
  • Automatic and user defined reconstruction of the healthy vessel shape according to its true 3D geometric shape
  • Quantification of lesion length and percentage stenosis.

CASS QVA for Research

CAAS QVA for Research (Quantitative Vascular Analysis) offers fast and intuitive analysis of peripheral vessels. When compared to its clinical counterpart QVA, the research package features additional functionality, dedicated for use in research studies.

  • Various methods for calibration; catheter, sphere, manual or automatically calculated based on geometric information
  • Vessel border detection based on novel algorithms.
  • Easy contour edits
  • Automatic and user defined reconstruction of the healthy vessel shape
  • Quantification of lesion length and percentage stenosis.
  • Evaluation of restenosis and edge effects on Drug Eluting Stents
  • Evaluation of overlap for Drug Eluting Balloons
  • Independent evaluation of multiple segments within one vessel part

DSA - Digital Subtraction Angiography

  • Greater enhancement of vessel edges
  • Improve contrast medium visibility without increasing contrast medium quantity
  • Application of Edge Enhancement algorithm
  • Repositioning of the mask, pixel shift


LVA RVA - Left and Right Ventricular Analysis software

This modular set up for Ventricular Analysis for Monoplane and Biplane Analysis, Multiple Volume Models and Regression Formulas makes it possible to fulfill all specific needs.

Technology and features are system/configuration dependent. Specifications subject to change without notice. For further details, please contact your EBIT sales representative.

CAAS LVA

CAAS LVA (Left Ventricular Analysis) offers fast and intuitive assessment of left ventricular function. The software provides automatic contour detection of the left ventricle as well as volume calculation and wall motion analysis. CAAS LVA is available for monoplane (RAO30º) and biplane (RAO30º + LAO60º) images.

  • Various methods for calibration; sphere, catheter, manual or automatically calculated based on geometric information
  • Ventricular border detection based on novel algorithms.
  • Easy contour edits
  • Multiple volume models and corresponding regression formula’s
  • Multiple wall motion models: Centerline, Radial, Regional, Slager

CAAS RVA

CAAS RVA (Right Ventricular Analysis) offers fast and intuitive assessment of right ventricular function. The software provides contour detection of the right ventricle as well as volume calculation and wall motion analysis.

  • Various methods for calibration; sphere, catheter, manual or automatically calculated based on geometric information
  • Ventricular border detection based on novel algorithms.
  • Easy contour edits
  • Multiple volume models and corresponding regression formula’s
  • Centerline wall motion model.
  • Extensively validated
  • Accurate and reproducible
  • Fast and user friendly
  • Easy integration with DICOM viewers
  • For patient care & (multi center) studies


CAAS A-Valve - Angiographic Valve Analysis

Determine the optimal C-arm position and accurately quantify aortic regurgitation

Recent developments in valve replacements have intensified the use of advanced imaging techniques in the cathlab. But why not use the imaging technology already available for guidance and post procedural evaluation? CAAS A-Valve uses X-ray images to assist physicians during valve replacements. The optimal projection module helps to limit contrast use by determining the optimal projection to place the valve. After the procedure, the peri-prosthetic regurgitation can be quantified on the spot.

Technology and features are system/configuration dependent. Specifications subject to change without notice. For further details, please contact your EBIT sales representative.

CAAS A-VALVE

X-ray images to determine the optimal projection

Why not use the imaging technology already available for guidance and post procedural evaluation during valve replacements? CAAS A-Valve uses X-ray images to assist physicians during valve replacements. The optimal projection module helps to limit contrast use by determining the optimal projection to place the valve.

Optimal Projection

    CAAS A-Valve’s optimal projection module requires only two aortograms to:
  • Determine the optimal C-arm position for valve placement
  • Reconstruct the aortic root in 3D
  • Measure aortic root dimensions

CAAS A-VALVE Qra

Guidance and post procedural evaluation during valve replacements

Scientific studies indicate that regurgitation after valve replacement has an effect on the long term clinical outcome. Thus, it is important to assess regurgitation directly after the procedure. Pie Medical Imaging has therefore developed the very first product that will visualize and quantify regurgitation on X-ray images. CAAS A-Valve uses X-ray images to assist physicians during valve replacements. The qRA module quantifies regurgitation immediately after placing the valve.

Quantification of Regurgitation

    The qRA module lets you:
  • Truly quantify aortic regurgitation during the procedure
  • All based on X-ray, no ultrasound or MRI required
  • CAAS A-Valve qRA is for research purposes only

Image Gallery

QCA 3D Bifurcation
QCA 3D Bifurcation
CAAS XA
CAAS XA
CAAS XA - Digital Subtraction Angiography
CAAS XA - Digital Subtraction Angiography
CAAS QCA - Quantitative Coronary Analysis sw
CAAS QCA - Quantitative Coronary Analysis sw
CAAS QCA - Quantitative Coronary Analysis 2D bifurcation
CAAS QCA - Quantitative Coronary Analysis 2D bifurcation
CAAS QCA - Quantitative Coronary Analysis research
CAAS QCA - Quantitative Coronary Analysis research
CAAS QCA - Quantitative Vascular Analysis sw - Research
CAAS QCA - Quantitative Vascular Analysis sw - Research
Digital Subtraction Angiography
Digital Subtraction Angiography
Digital Subtraction Angiography
Digital Subtraction Angiography
LVA RVA - Left&Right Ventricular Analysis sw
LVA RVA - Left&Right Ventricular Analysis sw Biplane Report
LVA RVA - Left&Right Ventricular Analysis sw
LVA RVA - Left&Right Ventricular Analysis sw
LVA RVA - Left&Right Ventricular Analysis sw
LVA RVA - Left&Right Ventricular Analysis sw
CAAS A-Valve - Angiographic Valve Assesment
CAAS A-Valve - Angiographic Valve Assesment
CAAS A-Valve - Angiographic Valve Analysis
CAAS A-Valve - Angiographic Valve Analysis
CAAS A-Valve QRA
CAAS A-Valve QRA
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